Direct Binding of Vx-809 to Human Cftr Nbd1

Molecular Structure and Function, Peter Gilgan Center for Research and Learning, Hospital for Sick Children (R.P.H, J.E.D., P.A.C., J.F.-K.) and Department of Biochemistry, University of Toronto (J.F.-K.), Toronto, ON, Canada; Center for Structural Biology (Z.Y., C.G.B.) and Department of Chemistry (C.G.B.), University of Alabama at Birmingham, Birmingham, AL, USA; Department of Physiology at UT Southwestern Medical Center at Dallas Forest Park, Dallas, TX, USA (L.M., P.J.T.). This article has not been copyedited and formatted. The final version may differ from this version. Molecular Pharmacology Fast Forward. Published on May 25, 2017 as DOI: 10.1124/mol.117.108373